BDBM224243 3-{6-(5-chloro-2- hydroxypyridin-3-yl)- 7-[(trans-4- methylcyclohexyl) methyl]-8-[(3r)-3- phenylmorpholin-4- yl]-7h-purin-2-yl}- 1,2,4-oxadiazol- 5(4h)-one::US9540377, 16.162
SMILES C[C@H]1CC[C@H](Cn2c(nc3nc(nc(-c4cc(Cl)cnc4O)c23)-c2noc(=O)[nH]2)N2CCOC[C@H]2c2ccccc2)CC1
InChI Key
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 224243
Affinity DataIC50: 0.847nMT: 2°CAssay Description:An HDM2 FRET assay was developed to assess the compounds' inhibitory activity towards binding of p53 protein. A truncated version of HDM2 with re...More data for this Ligand-Target Pair