BDBM224288 5-(6-(5-chloropyridin-3-yl)-7-(1- ((trans)-4-methylcyclohexyl)ethyl)- 8-((r)-3-phenylmorpholino)-7h- purin-2-yl)-1,3,4-oxadiazol-2(3h)- one::US9540377, 18.14
SMILES CC([C@H]1CC[C@H](C)CC1)n1c(nc2nc(nc(-c3cncc(Cl)c3)c12)-c1n[nH]c(=O)o1)N1CCOC[C@H]1c1ccccc1
InChI Key
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 224288
Affinity DataIC50: 0.620nMT: 2°CAssay Description:An HDM2 FRET assay was developed to assess the compounds' inhibitory activity towards binding of p53 protein. A truncated version of HDM2 with re...More data for this Ligand-Target Pair