BDBM225922 FXR_11

SMILES Brc1ccc2N(Cc3ccc(cc3)-c3nnn[nH]3)C(=O)C3(CCN(CC3)S(=O)(=O)c3cccs3)c2c1

InChI Key InChIKey=PDMCUTCDLHMYSW-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 225922   

TargetBile acid receptor(Human)
D3R/Abbott

LigandPNGBDBM225922(FXR_11)
Affinity DataIC50:  120nMpH: 7.4Assay Description:The assay buffer contained 50 mM HEPES (pH 7.4), 10 mM NaCl, 5 mM MgCl2 and 0.01% CHAPS. The reactions were incubated for 30 min in the presence of [...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails D3R
PDB3D3D Structure (crystal)