BDBM234502 US9353089, 135

SMILES CN1C(=N)NC(C1=O)(c1ccccc1)c1cccc(c1)-c1cccnc1

InChI Key InChIKey=PNSQCPQDRVOKMA-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 234502   

TargetBeta-secretase 1(Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM234502(US9353089, 135)
Affinity DataIC50:  1.68E+3nMpH: 4.0 T: 2°CAssay Description:The recombinant human BACE1, Cathepsin D, and Cathepsin E enzymes were purchased from R&D Systems (catalog numbers are 931-AS, 1014AS and 1294AS, res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPlasmepsin II(Plasmodium falciparum)
Saint Louis University

US Patent
LigandPNGBDBM234502(US9353089, 135)
Affinity DataIC50:  1.01E+3nMpH: 4.5 T: 2°CAssay Description:Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent