BDBM23820 (2R)-2-amino-3-{[(4-chlorophenyl)diphenylmethyl]sulfanyl}propanoic acid::S-Trityl-L-Cysteine (STLC) Analogue, 49

SMILES N[C@@H](CSC(c1ccccc1)(c1ccccc1)c1ccc(Cl)cc1)C(O)=O

InChI Key InChIKey=BSTXYLCINUXYQF-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 23820   Sort by

TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM23820((2R)-2-amino-3-{[(4-chlorophenyl)diphenylmethyl]su...)
Affinity DataIC50: 53.3nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 microtubule-stimulated ATPase activityMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM23820((2R)-2-amino-3-{[(4-chlorophenyl)diphenylmethyl]su...)
Affinity DataKi:  200nM ΔG°:  -9.13kcal/moleT: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
PubMed