BDBM241616 US9409915, 31::US9718820, Compound 31

SMILES CC(C)(C)c1cc(on1)-c1nc2nc(ccc2[nH]1)-c1ccccc1C(F)(F)F

InChI Key InChIKey=LGIRCIWUUXGYFJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 241616   

TargetTransient receptor potential M8 protein(Dog)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM241616(US9409915, 31 | US9718820, Compound 31)
Affinity DataIC50:  18nMT: 25°CAssay Description:HEK293 cells stably expressing canine TRPM8 were routinely grown as monolayers in Dulbecco's minimum essential medium supplemented with 10% FBS, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetTransient receptor potential M8 protein(Dog)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM241616(US9409915, 31 | US9718820, Compound 31)
Affinity DataIC50:  18nMT: 37°CAssay Description:HEK293 cells stably expressing canine TRPM8 were routinely grown as monolayers in Dulbecco's minimum essential medium supplemented with 10% FBS, 2 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent