BDBM255497 US10828301, Compound R940290::US9499493, R940290

SMILES CC(C)c1cccc(Nc2nc(Nc3cccc(OCC(=O)NCC(O)CO)c3)ncc2F)c1

InChI Key InChIKey=GTISGSPRWHOXJD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 255497   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Rigel Pharmceuticals

US Patent
LigandPNGBDBM255497(US10828301, Compound R940290 | US9499493, R940290)
Affinity DataIC50:  187nMAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Rigel Pharmceuticals

US Patent
LigandPNGBDBM255497(US10828301, Compound R940290 | US9499493, R940290)
Affinity DataIC50:  187nMpH: 7.4 T: 2°CAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent