BDBM259286 US9499547, 27

SMILES NC1(COc2ccc3ncc(-c4cc5ccccc5o4)n3n2)CCC1

InChI Key InChIKey=IFEKINMXPHDXRH-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 259286   

TargetGlutathione S-transferase P/Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) [T344D](Human)
Bayer Intellectual Property

US Patent

LigandBDBM259286(US9499547, 27)Copy SMILESCopy InChI

Affinity DataIC50: 29nMpH: 7.5 T: 2°CAssay Description:MKNK1-inhibitory activity at high ATP of compounds of the present invention after their preincubation with MKNK1 was quantified employing the TR-FRET...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/20/2017
Entry Details
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