BDBM259445 US9512114, 4

SMILES C[C@H](Nc1ncnc(N)c1-c1nnc(C)o1)c1cc2cccc(Cl)c2c(=O)n1C1CC1

InChI Key InChIKey=QJQRNZRTDKZVSY-JTQLQIEISA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 259445   

LigandPNGBDBM259445(US9512114, 4)
Affinity DataIC50:  1.47E+3nMT: 2°CAssay Description:PI3K (p110α/p85α) (h) is incubated in assay buffer containing 10 μM phosphatidylinositol 4,5-bisphosphate and MgATP (concentration as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Calitor Sciences

US Patent
LigandPNGBDBM259445(US9512114, 4)
Affinity DataIC50:  387nMT: 2°CAssay Description:PI3K (p120γ) (h) is incubated in assay buffer containing 10 μM phosphatidylinositol-4, 5-bisphosphate and MgATP (concentration as required)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM259445(US9512114, 4)
Affinity DataIC50:  11nMT: 2°CAssay Description:PI3K (p110δ/p85α) (h) is incubated in assay buffer containing 10 μM phosphatidylinositol-4, 5-bisphosphate and MgATP (concentration as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM259445(US9512114, 4)
Affinity DataIC50:  30nMT: 2°CAssay Description:PI3K (p1103/p85α) (h) is incubated in assay buffer containing 10 μM phosphatidylinositol-4, 5-bisphosphate and MgATP (concentration as requ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent