BDBM262110 6-Amino-2-(3-chloropropylsulfonimidoyl)-9-[(4-methoxyphenyl)methyl]-7H-purin-8-one::US11242345, Example 11::US9708325, 11

SMILES COc1ccc(Cn2c3nc(nc(N)c3[nH]c2=O)S(=N)(=O)CCCCl)cc1

InChI Key

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 262110   

TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM262110(6-Amino-2-(3-chloropropylsulfonimidoyl)-9-[(4-meth...)
Affinity DataEC50:  66nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM262110(6-Amino-2-(3-chloropropylsulfonimidoyl)-9-[(4-meth...)
Affinity DataEC50:  66nMAssay Description:HEK-Blue-hTLR7 cells were incubated at a density of 250,000˜450,000 cells/mL in a volume of 180 μL in a 96-well plate in Dulbecco's Mod...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent