BDBM262802 3-(3-methyl-1,4,6,7-tetrahydro-5H- pyrazolo[4,3-c]pyridin-5-yl)-2-(1H- tetrazol-5-yl)-6- trifluoromethyl)benzenesulfonamide::US9708336, 655

SMILES Cc1n[nH]c2CCN(Cc12)c1ccc(c(c1-c1nnn[nH]1)S(N)(=O)=O)C(F)(F)F

InChI Key InChIKey=CYRMEVWUFYIIFZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 262802   

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262802(3-(3-methyl-1,4,6,7-tetrahydro-5H- pyrazolo[4,3-c]...)
Affinity DataIC50:  7.80nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetVIM-1 metallo-beta-lactamase(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262802(3-(3-methyl-1,4,6,7-tetrahydro-5H- pyrazolo[4,3-c]...)
Affinity DataIC50:  0.225nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262802(3-(3-methyl-1,4,6,7-tetrahydro-5H- pyrazolo[4,3-c]...)
Affinity DataIC50:  0.985nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent