BDBM264047 2-[5-[(2,4- dimethylphenyl)methoxy]pyrazol- 1-yl]pyridine-4-carboxylic acid::US10173996, Example 132::US9604961, Example 132::US9714230, 132::US9908865, Example 132

SMILES Cc1ccc(COc2ccnn2-c2cc(ccn2)C(O)=O)c(C)c1

InChI Key InChIKey=ZQNXWEZQRNBWCU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 264047   

TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM264047(2-[5-[(2,4- dimethylphenyl)methoxy]pyrazol- 1-yl]p...)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM264047(2-[5-[(2,4- dimethylphenyl)methoxy]pyrazol- 1-yl]p...)
Affinity DataIC50: <100nMAssay Description:The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM264047(2-[5-[(2,4- dimethylphenyl)methoxy]pyrazol- 1-yl]p...)
Affinity DataIC50:  5.50E+3nMAssay Description:The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM264047(2-[5-[(2,4- dimethylphenyl)methoxy]pyrazol- 1-yl]p...)
Affinity DataIC50:  550nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2A was determined in 38-well plate format under the following reaction conditions: 2 nM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM264047(2-[5-[(2,4- dimethylphenyl)methoxy]pyrazol- 1-yl]p...)
Affinity DataIC50:  550nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent