BDBM266400 US9718790, I-0837

SMILES C[C@@H](Cn1c(=O)[nH]\c(=N/c2ccc(OCC3CC3)cc2)n(Cc2ccc(Cl)cc2)c1=O)C(O)=O

InChI Key

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 266400   

TargetP2X purinoceptor 3(RAT)
Shionogi

US Patent
LigandPNGBDBM266400(US9718790, I-0837)
Affinity DataIC50:  19nMpH: 7.5Assay Description:Rat P2X3 receptor gene (GenBank accession number NM_031075) was expressed in C6BU-1 cell. The cells stably expressing rat P2X3 were seeded in a 96-we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 3(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM266400(US9718790, I-0837)
Affinity DataIC50:  17nMAssay Description:Antagonist activity at P2X3 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM266400(US9718790, I-0837)
Affinity DataIC50:  17nMpH: 7.5Assay Description:Stably expressing cell line (C6BU-1 transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 3(RAT)
Shionogi

US Patent
LigandPNGBDBM266400(US9718790, I-0837)
Affinity DataIC50:  44nMpH: 7.5Assay Description:Rat P2X3 receptor gene (GenBank accession number NM_031075) was expressed in C6BU-1 cell. The cells stably expressing rat P2X3 were seeded in a 96-we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent