BDBM268512 N-(6-cyclopropyl-7-((1-(trifluoromethyl)cyclopentyl)methoxy)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)methanesulfonamide)::US9550775, 37::US9550775, 92

SMILES CS(=O)(=O)Nc1nnc2cc(OCC3(CCCC3)C(F)(F)F)c(cn12)C1CC1

InChI Key InChIKey=OMUXUABBGMYKDR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 268512   

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268512BDBM268512(US9550775, 92 | N-(6-cyclopropyl-7-((1-(trifluorom...)
Affinity DataIC50: 45nMpH: 7.2Assay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268512BDBM268512(US9550775, 92 | N-(6-cyclopropyl-7-((1-(trifluorom...)
Affinity DataIC50: 45.2nMpH: 7.2Assay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent