BDBM268517 N-(6-cyclopropyl-7-((3,4-dichlorophenoxy)methyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)azetidine-1-sulfonamide::US9550775, 41::US9550775, 96

SMILES Clc1ccc(OCc2cc3nnc(NS(=O)(=O)N4CCC4)n3cc2C2CC2)cc1Cl

InChI Key InChIKey=OFOYMFSQMQLWMW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 268517   

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268517BDBM268517(N-(6-cyclopropyl-7-((3,4-dichlorophenoxy)methyl)-[...)
Affinity DataIC50: 18.9nMpH: 7.2Assay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268517BDBM268517(N-(6-cyclopropyl-7-((3,4-dichlorophenoxy)methyl)-[...)
Affinity DataIC50: 19nMpH: 7.2Assay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent