BDBM268592 N-(6-cyclopropyl-7-((4-fluorobicyclo[2.2.2]octan-1-yl)methoxy)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)cyclopropanesulfonamide::US9550775, 115

SMILES FC12CCC(COc3cc4nnc(NS(=O)(=O)C5CC5)n4cc3C3CC3)(CC1)CC2

InChI Key InChIKey=AALOVLCPKUDXBS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 268592   

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268592BDBM268592(N-(6-cyclopropyl-7-((4-fluorobicyclo[2.2.2]octan-1...)
Affinity DataIC50: 21nMpH: 7.2Assay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent