BDBM26986 CHEMBL363707::HCO3-::SODIUM BICARBONATE::bicarbonate ion::hydrogen carbonate
SMILES OC([O-])=O
InChI Key InChIKey=BVKZGUZCCUSVTD-UHFFFAOYSA-M
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 80 hits for monomerid = 26986
Affinity DataKi: 8.20E+3nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 8.60E+3nMAssay Description:Inhibitory activity against human Carbonic anhydrase IXMore data for this Ligand-Target Pair
Affinity DataKi: 2.70E+5nMAssay Description:Inhibition of human recombinant CA7More data for this Ligand-Target Pair
Affinity DataKi: 2.70E+5nMAssay Description:Inhibition of human recombinant CA7More data for this Ligand-Target Pair
Affinity DataKi: 4.50E+5nMAssay Description:Inhibition of Stylophora pistillata carbonic anhydrase by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 5.00E+5nM ΔG°: -4.50kcal/molepH: 7.5 T: 25°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity Khalifah RG. The carbon dioxide hy...More data for this Ligand-Target Pair
Affinity DataKi: 7.50E+5nM ΔG°: -4.26kcal/molepH: 7.5 T: 25°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity Khalifah RG. The carbon dioxide hy...More data for this Ligand-Target Pair
Affinity DataKi: 7.50E+5nM ΔG°: -4.19kcal/molepH: 7.5 T: 20°CAssay Description:Inhibition of Vibrio cholerae alpha carbonic anhydrase preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 8.00E+5nMAssay Description:Inhibition of human recombinant CA6 by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 3.00E+6nM ΔG°: -3.38kcal/molepH: 7.5 T: 20°CAssay Description:Inhibition of Vibrio cholerae recombinant carbonic anhydrase gamma expressed in Escherichia coli DE3 cells preincubated for 15 mins by stopped-flow C...More data for this Ligand-Target Pair
TargetCarbonic anhydrase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
University of Florida
Curated by ChEMBL
University of Florida
Curated by ChEMBL
Affinity DataKi: 3.20E+6nMpH: 8.3Assay Description:Inhibition of Pseudomonas aeruginosa PAO1 type-2 beta-carbonic anhydrase psCA3 expressed in Escherichia coli Tuner BL21 (DE3) cells pre-incubated for...More data for this Ligand-Target Pair
TargetCarbonic anhydrase(Vibrio cholerae serotype O1 (strain ATCC 39315 / E...)
Universita Degli Studi Di Firenze
Universita Degli Studi Di Firenze
Affinity DataKi: 5.13E+6nM ΔG°: -3.07kcal/molepH: 7.5 T: 20°CAssay Description:Inhibition of Flaveria bidentis carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.70E+6nMAssay Description:Inhibitory activity against human Carbonic anhydrase IVMore data for this Ligand-Target Pair
Affinity DataKi: 5.90E+6nM ΔG°: -2.99kcal/molepH: 7.5 T: 20°CAssay Description:Inhibition of Vibrio cholerae carbonic anhydrase beta preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 6.60E+6nMAssay Description:Inhibition constant of anion against human carbonic anhydrase isozyme hCA IVMore data for this Ligand-Target Pair
Affinity DataKi: 6.60E+6nMAssay Description:Binding affinity against human cytosolic Carbonic anhydrase IVMore data for this Ligand-Target Pair
Affinity DataKi: 6.60E+6nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 6.60E+6nMAssay Description:Inhibition constant of anion against human carbonic anhydrase isozyme hCA IVMore data for this Ligand-Target Pair
Affinity DataKi: 6.60E+6nMAssay Description:Inhibition constant of anion against human carbonic anhydrase isozyme hCA IVMore data for this Ligand-Target Pair
Affinity DataKi: 7.81E+6nMAssay Description:Inhibition of Stylophora pistillata carbonic anhydrase 2 by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+7nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+7nMAssay Description:Inhibition constant of anion against human carbonic anhydrase isozyme hCA IMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+7nMAssay Description:Binding affinity against human cytosolic Carbonic anhydrase IMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+7nMAssay Description:Inhibition of human recombinant CA1 by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+7nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+7nM ΔG°: -2.57kcal/molepH: 7.5 T: 20°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+7nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase 1 after 15 mins by CO2 hydrase assay at pH 7.5More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+7nMpH: 8.3Assay Description:Inhibition of recombinant human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay at pH 8.3More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+7nM ΔG°: -2.57kcal/molepH: 7.5 T: 20°CAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+7nMAssay Description:Inhibitory constant against carbonic anhydrase IMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+7nMAssay Description:Inhibitory constant against carbonic anhydrase IMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+7nMAssay Description:Inhibitory activity against human carbonic anhydrase I expressed in Escherichia coliChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+7nMAssay Description:Inhibition of human recombinant wild type CA1 by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+7nMAssay Description:Inhibition constant of anion against human carbonic anhydrase isozyme hCA IMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+7nMAssay Description:Inhibition constant of anion against human carbonic anhydrase isozyme hCA IMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+7nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+7nMAssay Description:Inhibition of human carbonic anhydrase-1 at 20 degC preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.30E+7nMAssay Description:Inhibition constant of anion against human carbonic anhydrase isozyme hCA IXMore data for this Ligand-Target Pair
Affinity DataKi: 1.30E+7nMAssay Description:Inhibition constant of anion against human carbonic anhydrase isozyme hCA IXMore data for this Ligand-Target Pair
Affinity DataKi: 1.30E+7nMAssay Description:Binding affinity against human cytosolic Carbonic anhydrase IXMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+7nMAssay Description:Inhibitory activity against human Carbonic anhydrase IMore data for this Ligand-Target Pair
Affinity DataKi: 2.28E+7nMAssay Description:Inhibition of Astrosclera willeyana recombinant GST-tagged astrosclerin 3 expressed in Escherichia coli BL21-DE3-RIPL cells preincubated for 15 mins ...More data for this Ligand-Target Pair
TargetCarbonic anhydrase(Methanosarcina thermophila)
Istituto Di Biochimica Delle Proteine-Cnr
Curated by ChEMBL
Istituto Di Biochimica Delle Proteine-Cnr
Curated by ChEMBL
Affinity DataKi: 4.20E+7nMAssay Description:Inhibition of Methanosarcina thermophila recombinant gamma-CA by CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase(Methanosarcina thermophila)
Istituto Di Biochimica Delle Proteine-Cnr
Curated by ChEMBL
Istituto Di Biochimica Delle Proteine-Cnr
Curated by ChEMBL
Affinity DataKi: 4.20E+7nMAssay Description:Inhibition of archaeon Methanosarcina thermophila gamma-CA after 15 mins by stopped-flow/Co2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase(Methanosarcina thermophila)
Istituto Di Biochimica Delle Proteine-Cnr
Curated by ChEMBL
Istituto Di Biochimica Delle Proteine-Cnr
Curated by ChEMBL
Affinity DataKi: 4.20E+7nMAssay Description:Inhibitory constant against Zn-Cam (Methanosarcina thermophila)More data for this Ligand-Target Pair
TargetCarbonic anhydrase(Methanosarcina thermophila)
Istituto Di Biochimica Delle Proteine-Cnr
Curated by ChEMBL
Istituto Di Biochimica Delle Proteine-Cnr
Curated by ChEMBL
Affinity DataKi: 4.20E+7nMAssay Description:Inhibitory constant against Zn-Cam (Methanosarcina thermophila)More data for this Ligand-Target Pair
TargetCarbonic anhydrase(Methanosarcina thermophila)
Istituto Di Biochimica Delle Proteine-Cnr
Curated by ChEMBL
Istituto Di Biochimica Delle Proteine-Cnr
Curated by ChEMBL
Affinity DataKi: 4.20E+7nMAssay Description:Inhibition of Methanosarcina thermophila recombinant carbonic anhydrase gamma assessed as inhibition of CO2 hydration preincubated for 15 mins by Lin...More data for this Ligand-Target Pair
Affinity DataKi: 4.40E+7nMAssay Description:Inhibitory constant against carbonic anhydrase IVMore data for this Ligand-Target Pair
TargetCarbonic anhydrase(Methanobacterium thermoautotrophicum)
Universita Degli Studi Di Firenze
Curated by ChEMBL
Universita Degli Studi Di Firenze
Curated by ChEMBL
Affinity DataKi: 4.49E+7nMAssay Description:Inhibitory constant against methanoarchaeon Methanobacterium thermoautotrophicum (Cab)More data for this Ligand-Target Pair
TargetCarbonic anhydrase(Methanobacterium thermoautotrophicum)
Universita Degli Studi Di Firenze
Curated by ChEMBL
Universita Degli Studi Di Firenze
Curated by ChEMBL
Affinity DataKi: 4.49E+7nMAssay Description:Inhibitory constant against methanoarchaeon Methanobacterium thermoautotrophicum (Cab)More data for this Ligand-Target Pair