BDBM27618 3-(2-bromo-4-{1H-pyrazolo[3,4-c]pyridazin-3-ylmethyl}phenoxy)-5-methylbenzonitrile::pyrazolo[3,4-c]pyridazine, 10

SMILES Cc1cc(Oc2ccc(Cc3n[nH]c4nnccc34)cc2Br)cc(c1)C#N

InChI Key InChIKey=YYGZQXRLQMFHDH-UHFFFAOYSA-N

Data  2 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 27618   

TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto

LigandPNGBDBM27618(3-(2-bromo-4-{1H-pyrazolo[3,4-c]pyridazin-3-ylmeth...)
Affinity DataEC50: >100nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Roche Palo Alto

LigandPNGBDBM27618(3-(2-bromo-4-{1H-pyrazolo[3,4-c]pyridazin-3-ylmeth...)
Affinity DataEC50:  17nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair