BDBM279501 1-isopropyl-4-(6-(pyridin-4-yl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one::US10035777, Example 51

SMILES CC(C)N1CC(CC1=O)C(=O)Nc1ccc(cc1N)-c1ccncc1

InChI Key InChIKey=FWINUCOMTHZFBS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 279501   

TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 279501BDBM279501(US10035777, Example 51 | 1-isopropyl-4-(6-(pyridin...)
Affinity DataIC50: 783nMpH: 7.4 T: 2°CAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
US Patent