BDBM284926 1-(4-amino-5-(trifluoromethyl) pyrrolo[2,1-f][1,2,4]triazin-7-yl)-N- phenylpiperidine-3-carboxamide::US10023576, Example 118

SMILES Nc1ncnn2c(cc(c12)C(F)(F)F)N1CCCC(C1)C(=O)Nc1ccccc1

InChI Key InChIKey=FMDSZDJZBQFYPX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 284926   

LigandChemical structure of BindingDB Monomer ID 284926BDBM284926(US10023576, Example 118 | 1-(4-amino-5-(trifluorom...)
Affinity DataIC50: 214nMpH: 7.5 T: 2°CAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent