BDBM284990 N-[2,4-difluoro-5-(2-methyl-1-oxoisoquinolin- 4-yl)phenyl]methanesulfonamide::US10023592, Example 35

SMILES Cn1cc(-c2cc(NS(C)(=O)=O)c(F)cc2F)c2ccccc2c1=O

InChI Key InChIKey=DEEDYZRUGUHVLV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 284990   

TargetBromodomain-containing protein 4(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 284990BDBM284990(US10023592, Example 35 | N-[2,4-difluoro-5-(2-meth...)
Affinity DataIC50: 2.75E+3nMpH: 7.3Assay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent