BDBM28879 2-[(5Z)-5-[(3-{4-[(4-chlorophenyl)methoxy]phenyl}-1-phenyl-1H-pyrazol-4-yl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]ethane-1-sulfonic acid::cid_4601225::rhodanine derivative, 38

SMILES OS(=O)(=O)CCN1C(=S)S\C(=C/c2cn(nc2-c2ccc(OCc3ccc(Cl)cc3)cc2)-c2ccccc2)C1=O

InChI Key InChIKey=UEMVHDDFBLKUGI-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 28879   

TargetDual specificity protein phosphatase 3(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM28879(cid_4601225 | 2-[(5Z)-5-[(3-{4-[(4-chlorophenyl)me...)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant vaccina H1-related phosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM28879(cid_4601225 | 2-[(5Z)-5-[(3-{4-[(4-chlorophenyl)me...)
Affinity DataIC50: 460nMAssay Description:Inhibition of recombinant CD45More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 1(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM28879(cid_4601225 | 2-[(5Z)-5-[(3-{4-[(4-chlorophenyl)me...)
Affinity DataIC50: 460nMAssay Description:Inhibition of recombinant MKP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM28879(cid_4601225 | 2-[(5Z)-5-[(3-{4-[(4-chlorophenyl)me...)
Affinity DataIC50: 460nMAssay Description:Inhibition of recombinant PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 7(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM28879(cid_4601225 | 2-[(5Z)-5-[(3-{4-[(4-chlorophenyl)me...)
Affinity DataIC50: 620nMAssay Description:Inhibition of recombinant HePTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM28879(cid_4601225 | 2-[(5Z)-5-[(3-{4-[(4-chlorophenyl)me...)
Affinity DataIC50: 1.35E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetM-phase inducer phosphatase 1(Human)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM28879(cid_4601225 | 2-[(5Z)-5-[(3-{4-[(4-chlorophenyl)me...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of recombinant Cdc25aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Burnham Institute For Medical Research

LigandPNGBDBM28879(cid_4601225 | 2-[(5Z)-5-[(3-{4-[(4-chlorophenyl)me...)
Affinity DataIC50: 2.45E+3nMAssay Description:The fluorescence peptide cleavage assay was performed in a 96-well plate in which each reaction mixture contained MAPKKide, LF (List Biological Labor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2009
Entry Details Article
PubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM28879(cid_4601225 | 2-[(5Z)-5-[(3-{4-[(4-chlorophenyl)me...)
Affinity DataIC50: 7.21E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetBotulinum neurotoxin type A2 [1-425](Clostridium botulinum)
Burnham Institute For Medical Research

LigandPNGBDBM28879(cid_4601225 | 2-[(5Z)-5-[(3-{4-[(4-chlorophenyl)me...)
Affinity DataIC50: 2.00E+5nMAssay Description:The fluorescence peptide cleavage assay was performed in a 96-well plate in which each reaction mixture contained MAPKKide, LF (List Biological Labor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2009
Entry Details Article
PubMed