BDBM290354 10-(2-Fluoro-6-methoxyphenyl)-4-(piperidin-4-yl)pyrimido[1,2-b]indazol-2(1H)-one hydrochloride::US10098883, Example 97::US10668071, Example 97

SMILES COc1cccc(F)c1-c1cccc2nn3c(C4CCNCC4)cc(=O)[nH]c3c12

InChI Key InChIKey=JQAUZOWOZDCFCX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 290354   

TargetPlasminogen [101-181](Human)
Bayer

US Patent
LigandChemical structure of BindingDB Monomer ID 290354BDBM290354(US10098883, Example 97 | 10-(2-Fluoro-6-methoxyphe...)
Affinity DataIC50: 30nMpH: 7.0Assay Description:The test compounds were dissolved in 1% acetic acid and further complemented with an equal volume of DMSO. The resulting stock solutions were seriall...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetPlasminogen [101-181](Human)
Bayer

US Patent
LigandChemical structure of BindingDB Monomer ID 290354BDBM290354(US10098883, Example 97 | 10-(2-Fluoro-6-methoxyphe...)
Affinity DataIC50: 30nMAssay Description:The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent