BDBM292004 (E)-3-(3,5-difluoro-4-(2-((S)-3-fluoro-2-methylpropyl)-3,3-dimethyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)phenyl)acrylic acid (isomer 1)*::US10130617, Example 5

SMILES C[C@H](CF)CN1C(c2[nH]c3ccccc3c2CC1(C)C)c1c(F)cc(\C=C\C(O)=O)cc1F

InChI Key InChIKey=XTDHJGCTXMSPCY-RSEBSXLISA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 292004   

TargetEstrogen receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM292004((E)-3-(3,5-difluoro-4-(2-((S)-3-fluoro-2-methylpro...)
Affinity DataIC50:  570nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM292004((E)-3-(3,5-difluoro-4-(2-((S)-3-fluoro-2-methylpro...)
Affinity DataIC50:  200nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent