BDBM292619 N-((S)-2-(diethylamino)propyl)-2-((S)-2-(methylcarbamoyl)azetidin-1-yl)-6-(5-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidin-3-yl)isonicotinamide::US10100058, Example 275

SMILES CCN(CC)[C@@H](C)CNC(=O)c1cc(nc(c1)-c1cnn2ccc(nc12)-c1cccs1)N1CC[C@H]1C(=O)NC

InChI Key InChIKey=BKSPZDICBZFRLV-MBSDFSHPSA-N

Data  1 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 292619   

TargetCalcium/calmodulin-dependent protein kinase type II subunit delta(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM292619(N-((S)-2-(diethylamino)propyl)-2-((S)-2-(methylcar...)
Affinity DataEC50:  24.3nMAssay Description:CaMKII activity in neonatal rat ventricular myocytes (NRVM) was measured by monitoring the phosphorylation level of phospholamban using high-content ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCalcium/calmodulin-dependent protein kinase type II subunit delta(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM292619(N-((S)-2-(diethylamino)propyl)-2-((S)-2-(methylcar...)
Affinity DataIC50:  0.200nMAssay Description:The biochemical activity of recombinant CaMKIIδ was measured by monitoring the phosphorylation of a target peptide using Homogenous Time Resolve...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB