BDBM294045 US10106571, Example 2::US10106571, Example 23

SMILES CC(C)OC(=O)[C@H](C)NP(=O)(OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@@](F)(Cl)[C@@H]1O)Oc1ccccc1

InChI Key

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 294045   

TargetGenome polyprotein(Hepatitis C virus (HCV))
Medivir

US Patent
LigandPNGBDBM294045(US10106571, Example 2 | US10106571, Example 23)
Affinity DataEC50:  55nMAssay Description:The assay utilizes the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV))
Medivir

US Patent
LigandPNGBDBM294045(US10106571, Example 2 | US10106571, Example 23)
Affinity DataEC50:  5.10E+3nMAssay Description:The assay utilizes the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 2D6(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM294045(US10106571, Example 2 | US10106571, Example 23)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP2D6 using quinidine as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM294045(US10106571, Example 2 | US10106571, Example 23)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of human CYP2C9 using sulfaphenazole as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM294045(US10106571, Example 2 | US10106571, Example 23)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP1A2 using alpha-naphthoflavone as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM294045(US10106571, Example 2 | US10106571, Example 23)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of human CYP3A4 using ketoconazole as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed