BDBM295964 4-{2-methoxy- 4-[2-(2- methoxyphenyl) pyrrolidine- 1-carbonyl] phenyl}- 1H-pyrazole::US10112939, Example 6

SMILES COc1ccccc1C1CCCN1C(=O)c1ccc(-c2cn[nH]c2)c(OC)c1

InChI Key InChIKey=TYRYMGYKSPNYHM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 295964   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 295964BDBM295964(US10112939, Example 6 | 4-{2-methoxy- 4-[2-(2- met...)
Affinity DataIC50: 511nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent