BDBM29608 Bisphenol A (BPA)::Diphenylolpropane::US9688816, L
SMILES CC(C)(c1ccc(O)cc1)c1ccc(O)cc1
InChI Key InChIKey=IISBACLAFKSPIT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 20 hits for monomerid = 29608
Affinity DataIC50: 5.90E+3nMAssay Description:Antagonist activity at human pSG5-AR assessed as inhibition of dihydrotestosterone-induced effect by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 757nMAssay Description:Agonist activity at ERbeta (unknown origin) expressed in human HeLa cells assessed as transcriptional activation measured after 24 hrs by luciferase ...More data for this Ligand-Target Pair
Affinity DataEC50: 290nMAssay Description:Agonist activity at estrogen receptor in human MCF7 cells assessed as ERE-mediated transcriptional activity after 24 hrs by luciferase assayMore data for this Ligand-Target Pair
Affinity DataKd: 6.00E+5nMAssay Description:Binding affinity to human K-RAS by NMR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 1.80E+6nMAssay Description:Binding affinity to full-length Rheb (unknown origin) by NMR spectroscopic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 7.41E+4nMAssay Description:Inhibitory concentration against recombinant rat androgen receptor expressed in Escherichia coli using [3H]methyltrienolone (R 1881)More data for this Ligand-Target Pair
Affinity DataIC50: 490nMAssay Description:Competitive binding assays were performed by incubating rhER alpha (α) and beta 1 (β1) receptors with 10 nM [3H]estradiol (the radio ligand...More data for this Ligand-Target Pair
Affinity DataIC50: 670nMAssay Description:Competitive binding assays were performed by incubating rhER alpha (α) and beta 1 (β1) receptors with 10 nM [3H]estradiol (the radio ligand...More data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Binding affinity to human ERRgammaMore data for this Ligand-Target Pair
Affinity DataIC50: 504nMAssay Description:Binding affinity to GST-tagged human ER alpha ligand-binding domain by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at FLAG-tagged ERalpha (unknown origin) expressed in HEK293 cells assessed as induction of ER-alpha-mediated transcriptional activit...More data for this Ligand-Target Pair
Affinity DataEC50: 1.69E+3nMAssay Description:Selective estrogen receptor down-regulator activity at FLAG-tagged ERalpha (unknown origin) expressed in HEK293 cells assessed as induction of ERalph...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at FLAG-tagged ERalpha (unknown origin) expressed in HEK293 cells assessed as reduction in E2-induced ER-alpha-mediated transcrip...More data for this Ligand-Target Pair
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
University Of Chemistry And Technology Prague
Curated by ChEMBL
University Of Chemistry And Technology Prague
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of rabbit skeletal muscle microsomes SERCA1a by enzyme-coupled methodMore data for this Ligand-Target Pair
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 2(Rattus norvegicus)
University Of Chemistry And Technology Prague
Curated by ChEMBL
University Of Chemistry And Technology Prague
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of rat cerebellar microsomes SERCA2b by enzyme-coupled methodMore data for this Ligand-Target Pair
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
University Of Chemistry And Technology Prague
Curated by ChEMBL
University Of Chemistry And Technology Prague
Curated by ChEMBL
Affinity DataIC50: 2.33E+5nMAssay Description:Inhibition of rabbit microsomes SERCA1a by enzyme-coupled methodMore data for this Ligand-Target Pair
Affinity DataIC50: 904nMAssay Description:Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERalpha ligand binding domain expressed in Escherichia coli BL21alpha cells in...More data for this Ligand-Target Pair
Affinity DataIC50: 870nMAssay Description:Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERbeta ligand binding domain expressed in Escherichia coli BL21alpha cells inc...More data for this Ligand-Target Pair
Affinity DataEC50: 797nMAssay Description:Agonist activity at ERalpha (unknown origin) expressed in human HeLa cells assessed as transcriptional activation measured after 24 hrs by luciferase...More data for this Ligand-Target Pair
Affinity DataIC50: 13.1nMpH: 7.4 T: 2°CAssay Description:The receptor-binding assay was conducted using [3H]4-hydroxytamoxifen (4-OHT) as the radioligand. To estimate the binding affinity, the IC50 values (...More data for this Ligand-Target Pair