BDBM300107 N-[(1R,2S)-2- hydroxycyclobutyl]- 6-[4-(4-methoxy- 1H-pyrazolo[3,4- b]pyridin-3- yl)piperidin- 1-yl]-2-[(2R- tetrahydrofuran-2- ylmethoxy] pyrimidine- 4-carboxamide::US9593097, Example 488

SMILES COc1ccnc2[nH]nc(C3CCN(CC3)c3cc(nc(OC[C@H]4CCCO4)n3)C(=O)N[C@@H]3CC[C@@H]3O)c12

InChI Key

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 300107   

TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))

US Patent
LigandPNGBDBM300107(N-[(1R,2S)-2- hydroxycyclobutyl]- 6-[4-(4-methoxy-...)
Affinity DataKi:  0.0420nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent