BDBM300849 3-(6-((3-(4-(2-Methoxyethoxy)- 2-methylphenyl) benzo[b]thiophen-5- yl)methoxy)pyridin-3-yl) hex-4-ynoic acid::US10131648, Compound 47::US10195178, Compound 47::US9790198, Compound 47

SMILES COCCOc1ccc(-c2csc3ccc(COc4ccc(cn4)C(CC(O)=O)C#CC)cc23)c(C)c1

InChI Key InChIKey=SJMCOJMOWSZKOY-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 300849   

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 300849BDBM300849(3-(6-((3-(4-(2-Methoxyethoxy)- 2-methylphenyl) ben...)
Affinity DataEC50:  20nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 300849BDBM300849(3-(6-((3-(4-(2-Methoxyethoxy)- 2-methylphenyl) ben...)
Affinity DataEC50:  20nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2019
Entry Details
US Patent

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 300849BDBM300849(3-(6-((3-(4-(2-Methoxyethoxy)- 2-methylphenyl) ben...)
Affinity DataEC50:  20nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent