BDBM307796 N-[(trans-4-aminocyclohexyl)methyl]-5-chloro-4-[1-(3-fluorobenzyl)-1H-benzimidazol-6-yl]pyridin-2-amine::US9650358, Example 92

SMILES N[C@H]1CC[C@H](CNc2cc(c(Cl)cn2)-c2ccc3ncn(Cc4cccc(F)c4)c3c2)CC1

InChI Key InChIKey=UXOHMVLUDQQLTB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 307796   

TargetCyclin-dependent kinase 9(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 307796BDBM307796(US9650358, Example 92 | N-[(trans-4-aminocyclohexy...)
Affinity DataIC50: 39nMAssay Description:CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
US Patent