BDBM31086 1-[5-tert-butyl-2-(p-tolyl)pyrazol-3-yl]-3-[4-(2-morpholinoethoxy)-1-naphthyl]urea

SMILES Cc1ccc(cc1)n2c(cc(n2)C(C)(C)C)NC(=O)Nc3ccc(c4c3cccc4)OCCN5CCOCC5

InChI Key InChIKey=MVCOAUNKQVWQHZ-UHFFFAOYSA-N

PDB links: 9 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31086   

TargetProtein-tyrosine kinase 2-beta(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31086BDBM31086(1-[5-tert-butyl-2-(p-tolyl)pyrazol-3-yl]-3-[4-(2-m...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human recombinant N-terminal His-6-tagged thrombin cleavable fused PYK2 catalytic domain (residues Pro-416 to Glu-692) expressed in Sf9...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)