BDBM316254 US10294218, Example 82::US9617225, Example 82::[6-(4,5-Difluoro-2-methoxy-phenyl)-pyrimidin-4-yl]-(4-methoxy-3-nitro-phenyl)-amine

SMILES COc1ccc(Nc2cc(ncn2)-c2cc(F)c(F)cc2OC)cc1[N+]([O-])=O

InChI Key InChIKey=LOZZWEDPEBMZQV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 316254   

TargetCyclin-dependent kinase 9(Human)
Virostatics

US Patent
LigandChemical structure of BindingDB Monomer ID 316254BDBM316254(US9617225, Example 82 | [6-(4,5-Difluoro-2-methoxy...)
Affinity DataIC50: 1.00E+4nMAssay Description:The activity of the compounds described in the present invention can be determined by measuring the phosphorylation of a fluorescently-labeled peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Virostatics

US Patent
LigandChemical structure of BindingDB Monomer ID 316254BDBM316254(US9617225, Example 82 | [6-(4,5-Difluoro-2-methoxy...)
Affinity DataIC50: 1.00E+4nMAssay Description:The activity of the compounds described in the present invention can be determined by measuring the phosphorylation of a fluorescently-labeled peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent