BDBM321357 3-(6-but-2-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)-N,N-dimethyl-benzamide::US10183009, Example 32

SMILES CC=CCn1cc(-c2cccc(c2)C(=O)N(C)C)c2cc[nH]c2c1=O

InChI Key InChIKey=RJEMCUZKQLRUIS-SNAWJCMRSA-N

Data  1 IC50

PDB links: 3 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321357   

TargetBromodomain-containing protein 4 [42-168](Human)
Genentech

US Patent

LigandBDBM321357(3-(6-but-2-enyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-y...)Copy SMILESCopy InChI

Affinity DataIC50:  330nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to homogeneity. BRD4 binding and inhibition was assessed by monitoring the...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails US Patent
PDB3D Structure (crystal)
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