BDBM329194 4-(5-chloro-6-((1R)-1-phenylethoxy)-3-pyridinyl)-2-fluoro-5-methoxy-N-(methylsulfonyl)benzamide::Mixture of 4-(5-chloro-6-((1R)- 1-phenylethoxy)-3-pyridinyl)- 2-fluoro-5-methoxy-N- (methylsulfonyl)benzamide and 4-(5-chloro-6-((1S)-1- phenylethoxy)-3-pyridinyl)-2- fluoro-5-methoxy-N- (methylsulfonyl)benzamide::US9663508, Example 696::US9663508, Example 749

SMILES COc1cc(C(=O)NS(C)(=O)=O)c(F)cc1-c1cnc(O[C@H](C)c2ccccc2)c(Cl)c1

InChI Key InChIKey=WKWVYBKACCPJIK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 329194   

LigandChemical structure of BindingDB Monomer ID 329194BDBM329194(Mixture of 4-(5-chloro-6-((1R)- 1-phenylethoxy)-3-...)
Affinity DataIC50: 93nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 329194BDBM329194(Mixture of 4-(5-chloro-6-((1R)- 1-phenylethoxy)-3-...)
Affinity DataIC50: 93.6nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 329194BDBM329194(Mixture of 4-(5-chloro-6-((1R)- 1-phenylethoxy)-3-...)
Affinity DataIC50: 3.00E+3nMAssay Description:293 cells stably transfected with human Nav 1.5 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology syste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent