BDBM33216 pyrazolopyridine, (R)-14
SMILES NC[C@@H]1CN(CCO1)c1c(cnc2[nH]ncc12)-c1ccccc1
InChI Key InChIKey=YBRZCAKSBYWZTC-CYBMUJFWSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 33216
Affinity DataIC50: 5.90E+3nMpH: 7.4 T: 2°CAssay Description:CHK kinase function was measured in a DELFIA assay in order to monitor phosphorylation of a CDC25C peptide using a specific phospho antibody. The enz...More data for this Ligand-Target Pair
Affinity DataIC50: 700nMpH: 7.5 T: 2°CAssay Description:CHK kinase function was measured in a DELFIA assay in order to monitor phosphorylation of a CDC25C peptide using a specific phospho antibody. The enz...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
The Institute of Cancer Research
The Institute of Cancer Research
Affinity DatapH: 7.5 T: 2°CAssay Description:CDK1 kinase activity was measured in a DELFIA based HTScan CDK1/CycB kinase assay kit (Cell Signalling Technology) that monitors biotinylated substra...More data for this Ligand-Target Pair