BDBM332704 US10196378, Compound C07
SMILES CN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4ccc5ccccc5c4)cc3)cc2C(F)(F)F)CC1
InChI Key InChIKey=DALOQNGTFFDAFY-UHFFFAOYSA-N
Data 5 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 332704
TargetTyrosine-protein kinase ABL1 [T315I](Homo sapiens (Human))
The Regents of The University of Michigan
US Patent
The Regents of The University of Michigan
US Patent
Affinity DataKi: 119nMAssay Description:The biochemical assays were carried out using the non-phosphorylated kinase domain of c-Abl, Bcr-Abl in Ba/F3 cells is in the phosphorylated state.More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
The Regents of The University of Michigan
US Patent
The Regents of The University of Michigan
US Patent
Affinity DataKi: 155nMAssay Description:The biochemical assays were carried out using the non-phosphorylated kinase domain of c-Abl, Bcr-Abl in Ba/F3 cells is in the phosphorylated state.More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
The Regents of The University of Michigan
US Patent
The Regents of The University of Michigan
US Patent
Affinity DataKi: 155nMAssay Description:The biochemical assays were carried out using the non-phosphorylated kinase domain of c-Abl, Bcr-Abl in Ba/F3 cells is in the phosphorylated state.More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1 [Y253F](Homo sapiens (Human))
The Regents of The University of Michigan
US Patent
The Regents of The University of Michigan
US Patent
Affinity DataKi: >9.00E+3nMAssay Description:The biochemical assays were carried out using the non-phosphorylated kinase domain of c-Abl, Bcr-Abl in Ba/F3 cells is in the phosphorylated state.More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
The Regents of The University of Michigan
US Patent
The Regents of The University of Michigan
US Patent
Affinity DataKi: >2.70E+4nMAssay Description:The biochemical assays were carried out using the non-phosphorylated kinase domain of c-Abl, Bcr-Abl in Ba/F3 cells is in the phosphorylated state.More data for this Ligand-Target Pair