BDBM333988 (S)-1-(3-((9-ethyl-8-(6-methoxy- 5-methylpyridin-3-yl)-9H-purin- 6-yl)oxy)pyrrolidin-1-yl)propan- 1-one::US9730940, Compound 2-89

SMILES CCC(=O)N1CCC(C1)Oc1ncnc2n(CC)c(nc12)-c1cnc(OC)c(C)c1

InChI Key InChIKey=URFIWTIRLSPDOP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 333988   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM333988((S)-1-(3-((9-ethyl-8-(6-methoxy- 5-methylpyridin-3...)
Affinity DataIC50:  0.5nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4× Reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent