BDBM334092 8-(5-fluoro-6-methoxypyridin-3- yl)-9-methyl-6-{[(3S)-1- propanoylpyrrolidin-3-yl]oxy}- 9H-purine::US9730940, Compound 3-34

SMILES CCC(=O)N1CC[C@@H](C1)Oc1ncnc2n(C)c(nc12)-c1cnc(OC)c(F)c1

InChI Key InChIKey=BRCHZFYEKARLPL-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 334092   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Merck Sharp & Dohme

US Patent

LigandBDBM334092(8-(5-fluoro-6-methoxypyridin-3- yl)-9-methyl-6-{[(...)Copy SMILESCopy InChI

Affinity DataIC50: 9.30nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4× Reactio...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/23/2019
Entry Details
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