BDBM335568 5-((4-aminopiperidin-1-yl)methyl)-N-(3-(5-(chloromethyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolo[2,1-f][1,2,4]triazin-4-amine::US9737542, Example 11

SMILES NC1CCN(Cc2ccn3ncnc(Nc4cccc(c4)-c4noc(CCl)n4)c23)CC1

InChI Key InChIKey=LMOHKZXTMLTEKR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 335568   

TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 335568BDBM335568(US9737542, Example 11 | 5-((4-aminopiperidin-1-yl)...)
Affinity DataIC50: 550nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent