BDBM336235 1-(7-chloro-5-(pyridin-3-yl)indolin-1-yl)ethanone::US9745282, 43

SMILES CC(=O)N1CCc2cc(cc(Cl)c12)-c1cccnc1

InChI Key InChIKey=VMDXOQSIQWKVCE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 336235   

TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM336235(1-(7-chloro-5-(pyridin-3-yl)indolin-1-yl)ethanone ...)
Affinity DataIC50:  570nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM336235(1-(7-chloro-5-(pyridin-3-yl)indolin-1-yl)ethanone ...)
Affinity DataIC50:  7.40nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent