BDBM345424 US10202354, Example 89::[2-(4-cyclobutylpiperazin-1-yl)-4,5-dihydroimidazol-1-yl]-(4-methoxyphenyl)methanone

SMILES COc1ccc(cc1)C(=O)N1CCN=C1N1CCN(CC1)C1CCC1

InChI Key InChIKey=IOEHGJOVFKXLCI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345424   

TargetLysine-specific demethylase 2B(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 345424BDBM345424([2-(4-cyclobutylpiperazin-1-yl)-4,5-dihydroimidazo...)
Affinity DataIC50: 4.38nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent