BDBM346456 US10202378, Example 69::ethyl 4-[(3R)-3-hydroxy-3-(3-methylisoxazol-5-yl)but-1-ynyl]-2,6-dimethyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-3-carboxylate

SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#C[C@@](C)(O)c1cc(C)no1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 346456   

LigandPNGBDBM346456(US10202378, Example 69 | ethyl 4-[(3R)-3-hydroxy-3...)
Affinity DataIC50:  210nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM346456(US10202378, Example 69 | ethyl 4-[(3R)-3-hydroxy-3...)
Affinity DataIC50:  61nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent