BDBM351713 N-(4-chloro-3-(1-(2-(dimethylamino)ethyl)-1H-1,2,4-triazol-3-yl)thiophen-2-yl)-2-(2-oxo-6-(trifluoromethyl)quinolin-1(2H)-yl)acetamide::US9796706, Compound 157

SMILES CN(C)CCn1cnc(n1)-c1c(Cl)csc1NC(=O)Cn1c2ccc(cc2ccc1=O)C(F)(F)F

InChI Key InChIKey=JFLZYXQEUITDDU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 351713   

TargetMitogen-activated protein kinase 10(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 351713BDBM351713(US9796706, Compound 157 | N-(4-chloro-3-(1-(2-(dim...)
Affinity DataIC50: 100nMAssay Description:(1) Assay buffer #1 with 0.0025% Tween and 1 mM DTT was prepared using JNK buffer stock solution.(2) Assay buffer #2 with 0.025% BSA was prepared usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetMitogen-activated protein kinase 8(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 351713BDBM351713(US9796706, Compound 157 | N-(4-chloro-3-(1-(2-(dim...)
Affinity DataIC50: 100nMAssay Description:(1) Assay buffer #1 with 0.0025% Tween and 1 mM DTT was prepared using JNK buffer stock solution.(2) Assay buffer #2 with 0.025% BSA was prepared usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetMitogen-activated protein kinase 9(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 351713BDBM351713(US9796706, Compound 157 | N-(4-chloro-3-(1-(2-(dim...)
Affinity DataIC50: 100nMAssay Description:(1) Assay buffer #1 with 0.0025% Tween and 1 mM DTT was prepared using JNK buffer stock solution.(2) Assay buffer #2 with 0.025% BSA was prepared usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent