BDBM355971 (S)-1-(5-chloro-6- (2H-1,2,3-triazol-2- yl)pyridin-3-yl)-3-(2- fluoro-7-(1- methoxyethyl)pyrazo- lo[1,5-a]pyrimidin-6- yl)urea::US10442808, Example 95::US9815842, Example 95
SMILES CO[C@@H](C)c1c(NC(=O)Nc2cnc(c(Cl)c2)-n2nccn2)cnc2cc(F)nn12
InChI Key InChIKey=AUVLPBAMVALFTR-VIFPVBQESA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 355971
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1 [329-824](Human)
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 0.00200nMAssay Description:The assay employs a short peptide substrate labeled with the single fluorophore PT14 as a fluorescence lifetime probe sensitive to the cleavage state...More data for this Ligand-Target Pair
Affinity DataIC50: 0.00200nMAssay Description:IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ...More data for this Ligand-Target Pair