BDBM35732 sulfonamide deriv., 6

SMILES NS(=O)(=O)c1nnc(NC(=O)Cc2cccs2)s1

InChI Key InChIKey=KROUVPYNINHEBZ-UHFFFAOYSA-N

Data  9 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 35732   

TargetCarbonic anhydrase 7(Homo sapiens (Human))
Istanbul University

Curated by ChEMBL
LigandPNGBDBM35732(sulfonamide deriv., 6)
Affinity DataKi:  6.90nMAssay Description:Inhibition of human recombinant carbonic anhydrase 7 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM35732(sulfonamide deriv., 6)
Affinity DataKi:  7.40nM ΔG°:  -11.1kcal/moleT: 2°CAssay Description:An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM35732(sulfonamide deriv., 6)
Affinity DataKi:  7.60nM ΔG°:  -11.1kcal/moleT: 2°CAssay Description:An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM35732(sulfonamide deriv., 6)
Affinity DataKi:  11nMAssay Description:Inhibition of human carbonic anhydrase-9 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM35732(sulfonamide deriv., 6)
Affinity DataKi:  12nMAssay Description:Inhibition of human carbonic anhydrase-12 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM35732(sulfonamide deriv., 6)
Affinity DataKi:  51nM ΔG°:  -9.94kcal/molepH: 7.4 T: 2°CAssay Description:An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM35732(sulfonamide deriv., 6)
Affinity DataKi:  51nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Istanbul University

Curated by ChEMBL
LigandPNGBDBM35732(sulfonamide deriv., 6)
Affinity DataKi:  72nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Istanbul University

Curated by ChEMBL
LigandPNGBDBM35732(sulfonamide deriv., 6)
Affinity DataKi:  72nM ΔG°:  -9.74kcal/molepH: 7.4 T: 2°CAssay Description:An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed