BDBM35877 5,6-bis-(4-methoxy-phenyl)-pyrazine-2-carboxylicacid cyclohexylamide::5,6-diaryl-pyrazine-2-amide derivative, 6c::CHEMBL227840::N-cyclohexyl-5,6-bis(4-methoxyphenyl)pyrazine-2-carboxamide

SMILES COc1ccc(cc1)-c1ncc(nc1-c1ccc(OC)cc1)C(=O)NC1CCCCC1

InChI Key InChIKey=HOAIFTWDCHXJRY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35877   

TargetCannabinoid receptor 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM35877(5,6-bis-(4-methoxy-phenyl)-pyrazine-2-carboxylicac...)
Affinity DataIC50:  16.2nMAssay Description:Antagonist activity against human recombinant cannabinoid-1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM35877(5,6-bis-(4-methoxy-phenyl)-pyrazine-2-carboxylicac...)
Affinity DataIC50:  8nMpH: 7.4 T: 2°CAssay Description:A GTP-gamma-S CB1 functional assay was used to assess the potency of the pyrazine derivatives. [35S]GTP-gamma-S binding assays were performed at 30 d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed