BDBM360511 3-(3,5-dimethyl-1H-pyrazol-1-yl)-N- ((5-(3-methoxyphenyl)isoquinolin-8- yl)methyl)benzamide::US9828369, Example 68

SMILES COc1cccc(c1)-c1ccc(CNC(=O)c2cccc(c2)-n2nc(C)cc2C)c2cnccc12

InChI Key InChIKey=OAKUNIWTGQUSOV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 360511   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharpe & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 360511BDBM360511(3-(3,5-dimethyl-1H-pyrazol-1-yl)-N- ((5-(3-methoxy...)
Affinity DataIC50: 1.65E+3nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details
US Patent