BDBM360528 N-((5-(3-methoxyphenyl)isoquinolin- 8-yl)methyl)-1,3-diphenyl-1H- pyrazole-5-carboxamide::US9828369, Example 85

SMILES COc1cccc(c1)-c1ccc(CNC(=O)c2cc(nn2-c2ccccc2)-c2ccccc2)c2cnccc12

InChI Key InChIKey=SXLCVQHISUTHAZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 360528   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharpe & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 360528BDBM360528(N-((5-(3-methoxyphenyl)isoquinolin- 8-yl)methyl)-1...)
Affinity DataIC50: 3.58E+3nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details
US Patent