BDBM361967 9-ethyl-8-(2-methylpyrimidin-5- yl)-N-{[1-(pyrrolidin-1- ylcarbonyl)cyclopropyl]methyl}- 9H-purin-6-amine::US10221178, Compound 2-61

SMILES CCn1c(nc2c(NCC3(CC3)C(=O)N3CCCC3)ncnc12)-c1cnc(C)nc1

InChI Key InChIKey=XGSJRUATXOGZDS-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 361967   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Merck Sharp & Dohme

US Patent

LigandBDBM361967(9-ethyl-8-(2-methylpyrimidin-5- yl)-N-{[1-(pyrroli...)Copy SMILESCopy InChI

Affinity DataIC50: 93nMAssay Description:Compounds are serially diluted (3-fold in 100% DMSO) across a 384-well polypropylene source plated from column 3 to column 12 and column 13 to column...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/27/2019
Entry Details
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